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[1]梁 爽,宾 琴,柏正武,等.壳聚糖衍生物手性固定相的制备及其分离性能[J].武汉工程大学学报,2017,39(04):320-325.[doi:10. 3969/j. issn. 1674?2869. 2017. 04. 003]
 LIANG Shuang,BIN Qing,BAI Zhengwu,et al.Preparation and Enantioseparation Performance of Chiral Stationary Phases Derived from Chitosan Derivatives[J].Journal of Wuhan Institute of Technology,2017,39(04):320-325.[doi:10. 3969/j. issn. 1674?2869. 2017. 04. 003]
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壳聚糖衍生物手性固定相的制备及其分离性能(/HTML)
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《武汉工程大学学报》[ISSN:1674-2869/CN:42-1779/TQ]

卷:
39
期数:
2017年04期
页码:
320-325
栏目:
化学与化学工程
出版日期:
2017-10-14

文章信息/Info

Title:
Preparation and Enantioseparation Performance of Chiral Stationary Phases Derived from Chitosan Derivatives
文章编号:
20170403
作者:
梁 爽宾 琴柏正武陈 伟*
武汉工程大学化学与环境工程学院,湖北 武汉 430205
Author(s):
LIANG Shuang BIN Qing BAI Zhengwu CHEN Wei*
School of Chemistry and Environmental Engineering,Wuhan Institute of Technology,Wuhan 430205,China
关键词:
壳聚糖苯甲酰化手性分离材料高效液相色谱手性识别
Keywords:
chitosan benzoylation chiral separation material high performance liquid chromatography chiral recognition
分类号:
O636.9
DOI:
10. 3969/j. issn. 1674?2869. 2017. 04. 003
文献标志码:
A
摘要:
壳聚糖;苯甲酰化;手性分离材料;高效液相色谱;手性识别
Abstract:
To develop new materials for enantioseparation, chitosan bis(3,5-dimethylphenylcarbamate)-(benzamide) and chitosan bis(4-methylphenylcarbamate)-(benzamide) were prepared. With regard to the benzoylation of chitosan, the complete benzoylation was achieved when benzoic anhydride was fed at six equivalences of the glucosamine. The two chitosan derivatives were coated on the surface of aminopropyl silica gel, then the corresponding chiral stationary phases were obtained. The enantioseparation performance of the two chiral stationary phases was evaluated with 12 chiral compounds by high performance liquid chromatography in the mobile phases of n-hexane/isopropanol, n-hexane/ethanol and n-hexane/methanol/ethanol. The results show that the chiral stationary phases possess good chiral recognition capability towards the analytes. Meanwhile, the influence of the composition of the mobile phase on enantioseparation was discussed according to the separation results.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2017-05-09 基金项目:国家自然科学基金(51373127) 作者简介:梁 爽,硕士研究生. E-mail: 398520795@qq.com
更新日期/Last Update: 2017-08-04