|本期目录/Table of Contents|

[1]朱胤霈,卢轶男,印建国,等.维生素E分子印迹聚合物的二步溶胀法制备[J].武汉工程大学学报,2020,42(02):134-138，142.[doi:10.19843/j.cnki.CN42-1779/TQ.201807001]
　ZHU Yinpei,LU Yinan,YIN Jianguo,et al.Preparation of Vitamin E Molecularly Imprinted Polymers by Two-Step Swelling Method[J].Journal of Wuhan Institute of Technology,2020,42(02):134-138，142.[doi:10.19843/j.cnki.CN42-1779/TQ.201807001]
点击复制

维生素E分子印迹聚合物的二步溶胀法制备(/HTML)
分享到：

《武汉工程大学学报》[ISSN:1674-2869/CN:42-1779/TQ]

卷:
42
期数:
2020年02期
页码:
134-138，142
栏目:
化学与化学工程
出版日期:
2021-01-26

文章信息/Info

Title:
Preparation of Vitamin E Molecularly Imprinted Polymers by Two-Step Swelling Method
文章编号:
1674 - 2869（2020）02 - 0134 - 05
作者:
朱胤霈1; 卢轶男1; 印建国2; 张佑红*1; 田　莉1
1.武汉工程大学化工与制药学院，湖北 武汉 430205；2.江苏玺鑫维生素有限公司，江苏 宿迁 223600
Author(s):
ZHU Yinpei1;  LU Yinan1; YIN Jianguo2; ZHANG Youhong*1; TIAN Li1
1. School of Chemical Engineering and Pharmacy，Wuhan Institute of Technology，Wuhan 430205，China；2. Jiangsu Xixin Vitamin Co.，Ltd, Suqian 223600, China
关键词:
VE; 分子印迹聚合物; 二步溶胀聚合法; 吸附分离
Keywords:
vitamin E;  molecularly imprinted polymers;  two-step swelling polymerization method;  adsorption and separation
分类号:
TQ420.6
DOI:
10.19843/j.cnki.CN42-1779/TQ.201807001
文献标志码:
A
摘要:
为了提高工业上分离提纯天然维生素E的效率，以聚苯乙烯微球为种球，维生素E（VE）为模板分子，甲基丙烯酸为功能单体，二甲基丙烯酸乙二醇酯为交联剂，采用二步溶胀聚合法制备了VE分子印迹聚合物，利用红外光谱仪，扫描电子显微镜表征印迹聚合物的组成和微结构并采用静态吸附实验分析印迹聚合物对VE的结合能力，结果表明，印迹聚合物具有良好的球形度和吸附效果，对VE的吸附量达到了38.12 mg/g。采用Langmuir模型与Freundlich模型对等温吸附曲线进行拟合，发现Freundlich模型能更好的拟合实验数据；Scatchard分析表明印迹聚合物中存在两类不同的结合位点。此方法合成的印迹聚合物微球对VE有较好的结合性能，可应用于VE的工业分离提纯。
Abstract:
To purify the Vitamin （VE）， we synthesized a molecularly imprinted polymer （MIP） via a two-step swelling method， in the presence of polystyrene microspheres as the substrate， methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the cross-linker. The composition and microstructures of the MIPs were characterized by infrared spectroscopy and scanning electron microscopy. Their performances in VE purification were investigated by adsorption experiments. It is found that the MIP possesses good sphericity and a high adsorption capacity （38.12 mg/g） in chloroform solution. The MIP presents a higher capacity than the non-imprinted polymer （NIP） towards VE. The Freundlich model is a better equation to describe the VE adsorption onto the MIP than the Langmuir model. The synthesized MIPs is suitable for the separation and purification of VE in industry.

参考文献/References:

［1］　武文华，曹玉平，刘凯，等. 天然维生素E提取工艺研究现状［J］. 中国油脂，2016，41（8）：88-91. ［2］　贺灵芝，旷文安，黄镇. 山茶籽油脱臭馏出物中维生素E的萃取分离研究［J］. 粮食与油脂，2018，3（4）：39-42. ［3］　HUANG S Y， XU J Q，ZHENG J T，et al. Synthesis and application of magnetic molecularly imprinted polymers in sample preparation ［J］. Analytical and Bioanalytical Chemistry，2018，410：3991-4014. ［4］　PETER A. Special issue on the 8th international conference on molecular imprinting［J］. Monatshefte für Chemie Chemical Monthly，2015，146（3）：421. ［5］　LIU J B ，DAI Z Q，LI B ， et al．Utilization of the oretical studies of the imprinting ratio to guide experimental research into the molecular imprinted polymers formed using enrofloxacin and methacrylic acid ［J］. Journal of Molecular Nodeling，2014（20）：2456-2466. ［6］　RENKECZ T， MISTLBERGER G，PAWLAK M，et al. Molecularly imprinted polymer microspheres containing photoswitchable spiropyran-based binding sites［J］. Applied Material and Interfaces，2013，5（17）：8537- 8545. ［7］　XU C G，UDDIN K A，SHEN X T，et al. Photoconjugation of molecularly imprinted polymer with magnetic nanoparticles ［J］. Applied Material and Interfaces，2013，5（11）： 5208-5213. ［8］　 LIU Z C，HU Z Y， LIU Y，et al. Monodisperse magnetic ion imprinted polymeric microparticles prepared by RAFT polymerization based on gamma Fe2O3 @meso-SiO2 nanospheres for selective solid-phase extraction of Cu（II） in water samples［J］. RSC Advances，2015，5（65）：52369-52381. ［9］　LEE M H，THOMAS J L， TSENG H Y，et al. Sensing of digestive proteins in saliva with a molecularly imprinted poly （ethylene-co-vinyl alcohol） thin film coated quartz crystal microbalance sensor ［J］. Applied Material and Interfaces，2011（3）：3064-3071. ［10］　小宫山真，竹内俊文，务川高志，等. 分子印迹学―从基础到应用［M］. 吴世康，汪鹏飞，译. 北京： 科学出版社，2006： 15. ［11］ HOSOYA K，OHTA H，YOSHIZAKO K，et al. Preparation of uniformly sized polymeric separation media potentially suitable for small-scale high-performance liquid chromatography and/or capillary electrochromatography ［J］. Journal of Chromatography A， 1999，853（1/2）： 11-20. ［12］ ZHANG L Y，CHENG G X，FU C. Molecular selectivity of tyrosine imprinted polymers prepared by seed swelling and suspension polymerization ［J］. Polymer International， 2002，51（8）： 687-692. ［13］ ZUO H M，LI Y，LI L，et al. Preparation of chloramphenicol molecularly imprinted polymer microspheres by two step seed swelling method and its recognition performance［J］. Chemical Industry and Engineering Progress，2011，30（3）：589-596. ［14］ LUZ A D，UISON de SOUZA SM de A， LUZ C D，et al. Rezende multicomponent adsorption and desorption of btx compounds using coconut shell activated carbon： experiments，mathematical modeling，and numerical simulation［J］. Industrial and Engineering Chemistry Research，2013，52（23）：7895-7911. ［15］ ADIANA D L，SELENE M S，CLEUZIR L，et al. Multicomponent adsorption and desorption of btx compounds using coconut shell activated carbon： experiments， mathematical modeling， and numerical simulation ［J］. Industrial and Engineering Chemistry Research， 2013，52：7895-7911. ［16］ ANNAMMA K M， MATHEW B. Design of 2，4-Dichlorophenoxyacetic acid imprinted polymer with high specificity and selectivity ［J］. Analytical Chemistry，2011（2）： 131-140.

相似文献/References:

[1]张佑红,钟季良,李卫朋,等.分子印迹聚合物对林可霉素的静态吸附[J].武汉工程大学学报,2015,37(06):10.[doi:10. 3969/j. issn. 1674-2869. 2015. 06. 003]
　,HEN,et al.Ｓｔａｔｉｃ ａｄｓｏｒｐｔｉｏｎ ｏｆ ｍｏｌｅｃｕｌａｒｌｙ ｉｍｐｒｉｎｔｅｄ ｐｏｌｙｍｅｒ ｔｏ Ｌｉｎｃｏｍｙｃｉｎ[J].Journal of Wuhan Institute of Technology,2015,37(02):10.[doi:10. 3969/j. issn. 1674-2869. 2015. 06. 003]

备注/Memo

备注/Memo:
收稿日期：2018-07-02作者简介：朱胤霈，硕士研究生。E-mail：502417206@qq.com*通讯作者：张佑红，博士，教授，博士研究生导师。E-mail：youhong@aliyun.com引文格式：朱胤霈，卢轶男，印建国，等. 维生素E 分子印迹聚合物的二步溶胀法制备［J］. 武汉工程大学学报，2020，42（2）：134-138，142.
更新日期/Last Update: 2020-06-19