新型咪唑啉酮衍生物的合成研究-《武汉工程大学学报》

文章信息/Info

Title:: Synthesis of novel 2arylheterocyclicamino3aryl5
arylidene4Himidazolin4one Derivatives

文章编号:: 16742869(2010)03003703

作者:: 王勇; 冯菊红; 巨修练*; 武汉工程大学化工与制药学院,湖北省新型反应器与绿色化学工艺重点实验室，湖北武汉 430074

Author(s):: WANG Yong; FENG Juhong; JU Xiulian; Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical Technology,
School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430074, China

关键词:: 咪唑啉酮衍生物; 合成; AzaWittig反应

Keywords:: imidazolinone derivatives; synthesis; AzaWittig raection

分类号:: O626.23

DOI:: -

文献标志码:: A

摘要:: 由芳醛经Staudinger反应制备得到的膦亚胺，与芳杂环伯胺通过串联的Azawittig反应，得到八个未见文献报道的咪唑啉酮衍生物．目标化合物的结构经HRMS、1H NMR确证；并发现碳二亚胺与芳杂环伯胺加成后再关环得到咪唑啉酮环时有一定的选择性．

Abstract:: The standinger reaction of aromatic aldehyde provided iminophoshorane. The eight novel imidazolinone derivatives were synthesized by a tandem azaWittig reaction of iminophosphorane with heteroatom primary arylamine. The structures of the compounds were confirmed by HRMS and 1H NMR. The cyclizing reaction of imidazolinones has a certain selectivity.

参考文献/References:

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